| DATE | OPPONENT | SCORE | RECORD/BIG 12 |
| Nov 4 | California All-Stars (ex) | W 82-77 | 1-0 |
| Nov 11 | Global Sports (ex) | L 80-78 | 1-1 |
| Nov 17 | Alcorn State (Sooner Holiday Classic) |
W 75-56 | 1-0 |
| Nov 18 | La Salle (Sooner Holiday Classic) |
W 89-72 | 2-0 |
| Nov 24 | Montana State (Big Island Invitational) |
W 84-76 | 3-0 |
| Nov 25 | Tulane (Big Island Invitational) |
W 83-69 | 4-0 |
| Nov 26 | Orgegon State (Big Island Invitational) |
W 78-60 | 5-0 |
| Dec 2 | at Mississippi | L 60-55 | 5-1 |
| Dec 9 | North Texas | W 100-72 | 6-1 |
| Dec 16 | Coppin State | W 103-49 | 7-1 |
| Dec 20 | Southwest Texas State | W 96-48 | 8-1 |
| Dec 23 | Arkansas | W 88-79 OT | 9-1 |
| Dec 29 | Oral Roberts (Touchstone Energy All-College Tournament) |
W 84-51 | 10-1 |
| Dec 30 | SMU (Touchstone Energy All-College Tournament) |
W 79-78 OT | 11-1 |
| Jan 6 | at Iowa State* | L 100-80 | 11-2 / 0-1 |
| Jan 9 | Texas A&M* | W 78-65 | 12-2 / 1-1 |
| Jan 13 | Kansas* | L 69-61 | 12-3 / 1-2 |
| Jan 16 | at Texas Tech* | L 60-59 | 12-4 / 1-3 |
| Jan 20 | at Kansas State* | W 64-63 OT | 13-4 / 2-3 |
| Jan 24 | Texas* | W 75-68 | 14-4 / 3-3 |
| Jan 27 | Nebraska* | W 77-66 | 15-4 / 4-3 |
| Jan 31 | at Baylor* | W 65-51 | 16-4 / 5-3 |
| Feb 3 | at Texas A&M* | W 72-63 | 17-4 / 6-3 |
| Feb 7 | Texas Tech* | W 80-72 | 18-4 / 7-3 |
| Feb 10 | at Texas* | W 75-54 | 19-4 / 8-3 |
| Feb 14 | at Oklahoma State* | L 72-44 | 19-5 / 8-4 |
| Feb 17 | Baylor* | W 82-60 | 20-5 / 9-4 |
| Feb 19 | at Missouri* | W 63-61 | 21-5 / 10-4 |
| Feb 24 | at Maryland | L 68-60 | 21-6 / 10-4 |
| Feb 28 | Colorado* | W 86-67 | 22-6 / 11-4 |
| Mar 3 | Oklahoma State* | W 68-56 | 23-6 / 12-4 |
| Mar 8 | Bye Round 1 - Big 12 Championship |
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| Mar 9 | Missouri Round 2 - Big 12 Championship* |
W 67-65 | 24-6 / 13-4 |
| Mar 10 | Kansas Round 3 - Big 12 Championship* |
W 62-57 | 25-6 / 14-4 |
| Mar 11 | Texas Big 12 Championship |
W 54-45 | 26-6 / 15-4 |
| Mar 16 | Indiana State NCAA First Round |
L 70-68 OT | 26-7 / 15-4 |