IndianaIndiana| DATE | OPPONENT | SCORE | RECORD |
| Nov 4 | Athletes In Action (Ex) | W 105-59 | 1-0 |
| Nov 14 | Nike Elite (Ex) | W 98-76 | 2-0 |
| Nov 18 | at Charlotte | W 65-61 | 1-0 |
| Nov 21 | at Alaska Anchorage Great Alaska Shootout |
W 101-66 | 2-0 |
| Nov 23 | Marquette Great Alaska Shootout |
L 49-50 | 2-1 |
| Nov 24 | Texas Great Alaska Shootout |
W 76-71 | 3-1 |
| Nov 28 | at North Carolina Big Ten/ACC Challenge |
W 79-66 | 4-1 |
| Dec 1 | at Southern Illinois | L 72-60 | 4-2 |
| Dec 4 | Notre Dame | W 76-75 | 5-2 |
| Dec 8 | Ball State | W 74-61 | 6-2 |
| Dec 15 | Miami Orange Bowl Classic |
L 58-53 | 6-3 |
| Dec 22 | Kentucky (RCA Dome) | L 52-66 | 6-4 |
| Dec 28 | Eastern Washington Hoosier Classic |
W 87-66 | 7-4 |
| Dec 29 | Butler Hoosier Classic |
L 64-66 | 7-5 |
| Jan 2 | at Northwestern* | W 59-44 | 8-5 / 1-0 |
| Jan 5 | Penn State* | W 61-54 | 9-5 / 2-0 |
| Jan 8 | Michigan State* | W 83-65 | 10-5 / 3-0 |
| Jan 13 | at Iowa* | W 73-66 | 11-5 / 4-0 |
| Jan 19 | at Ohio State* | L 67-73 | 11-6 / 4-1 |
| Jan 23 | at Penn State* | W 85-51 | 12-6 / 5-1 |
| Jan 26 | Illinois* | W 88-57 | 13-6 / 6-1 |
| Jan 31 | Purdue* | W 66-52 | 14-6 / 7-1 |
| Feb 2 | at Minnesota* | L 88-74 | 14-7 / 7-2 |
| Feb 5 | Iowa* | W 79-51 | 15-7 / 8-2 |
| Feb 9 | Louisville | W 77-62 | 16-7 / 8-2 |
| Feb 13 | Wisconsin* | L 64-63 | 16-8 / 8-3 |
| Feb 17 | at Michigan* | W 75-55 | 17-8 / 9-3 |
| Feb 20 | Ohio State* | W 63-57 | 18-8 / 10-3 |
| Feb 24 | at Michigan State* | L 57-54 | 18-9 / 10-4 |
| Feb 26 | at Illinois* | L 70-62 | 18-10 / 10-5 |
| Mar 2 | Northwestern* | W 79-67 | 19-10 / 11-5 |
| Mar 8 | Michigan State* Big 10 Tournament Round 2* |
W 67-56 | 20-10 / 12-5 |
| Mar 9 | Iowa* Big 10 Semifinals* |
L 62-60 | 20-11 / 12-6 |
| Mar 14 | Utah NCAA First Round |
W 75-56 | 21-11 / 12-6 |
| Mar 16 | UNC-Wilmington NCAA Second Round |
W 76-67 | 22-11 / 12-6 |
| Mar 21 | Duke NCAA Third Round |
W 74-73 | 23-11 / 12-6 |
| Mar 23 | Kent State NCAA Fourth Round |
W 81-69 | 24-11 / 12-6 |
| Mar 30 | Oklahoma NCAA Semifinal Round |
W 73-64 | 25-11 / 12-6 |
| Apr 1 | Maryland NCAA Championship Round |
L 52-64 | 25-12 / 12-6 |