| DATE | OPPONENT | SCORE | RECORD/BIG 12 |
| Nov 9 | USAO (Exh) | W 113-59 | 1-0 |
| Nov 13 | Global Sports (Exh) | W 80-63 | 2-0 |
| Nov 19 | Northwestern State | W 91-53 | 1-0 |
| Nov 23 | Arkansas-Little Rock | W 90-65 | 2-0 |
| Nov 27 | Sam Houston State | W 73-57 | 3-0 |
| Nov 29 | at SMU | W 76-57 | 4-0 |
| Dec 4 | Washington State | W 81-29 | 5-0 |
| Dec 7 | Syracuse Jimmy V Classic Madison Square Garden |
W 74-60 | 6-0 |
| Dec 10 | Alabama-Birmingham | W 86-73 | 7-0 |
| Dec 18 | at UNLV Las Vegas Showdown |
W 79-67 | 8-0 |
| Dec 21 | Northwestern Oklahoma | W 92-35 | 9-0 |
| Dec 28 | Gonzaga Touchstone Energy All-College Classic |
L 78-75 | 9-1 |
| Jan 3 | at Texas A&M-Corpus Christi | W 86-61 | 10-1 |
| Jan 8 | at Texas Tech* | W 76-66 | 11-1 / 1-0 |
| Jan 11 | Missouri* | W 78-68 | 12-1 / 2-0 |
| Jan 15 | Iowa State* | W 83-73 | 13-1 / 3-0 |
| Jan 17 | at Texas* | L 75-61 | 13-2 / 3-1 |
| Jan 22 | Baylor* | W 82-53 | 14-2 / 4-1 |
| Jan 24 | at Oklahoma* | L 67-57 | 14-3 / 4-2 |
| Jan 30 | at Colorado* | W 104-86 | 15-3 / 5-2 |
| Feb 2 | Kansas State* | W 77-57 | 16-3 / 6-2 |
| Feb 5 | at Baylor* | W 81-63 | 17-3 / 7-2 |
| Feb 7 | Oklahoma* | W 79-67 | 18-3 / 8-2 |
| Feb 12 | at Texas A&M* | W 66-59 | 19-3 / 9-2 |
| Feb 19 | Texas Tech* | W 85-56 | 20-3 / 10-2 |
| Feb 22 | at Nebraska* | L 74-67 | 20-4 / 10-3 |
| Feb 27 | at Kansas* | L 81-79 | 20-5 / 10-4 |
| Mar 2 | Texas A&M* | W 69-63 | 21-5 / 11-4 |
| Mar 5 | Texas* | L 74-73 | 21-6 / 11-5 |
| Mar 10 | Round One - Big 12 Championship | Bye | |
| Mar 11 | Quarterfinals - Big 12 Championship Colorado* |
W 87-85 | 22-6 / 12-5 |
| Mar 12 | Semifinals - Big 12 Championship Kansas* |
W 78-75 | 23-6 / 13-5 |
| Mar 13 | Finals - Big 12 Championship Texas Tech* |
W 72-68 | 24-6 / 14-5 |
| Mar 18 | Round 1 - NCAA Tournament SE Louisiana |
W 63-50 | 25-6 / 14-5 |
| Mar 20 | Round 2 - NCAA Tournament Southern Illinois |
W 85-77 | 26-6 / 14-5 |
| Mar 24 | Regional Semifinals - NCAA Tournament Arizona |
L 79-78 | 26-7 / 14-5 |