| DATE | OPPONENT | SCORE | RECORD/BIG 12 |
| Nov 10 | Cameron (Exhibition) |
W 91-56 | 1-0 |
| Nov 13 | Central Oklahoma (Exhibition) |
W 95-71 | 2-0 |
| Nov 20 | Cal State Northridge | W 82-72 | 1-0 |
| Nov 25 | High Point (Great Alaska Shootout) |
W 93-65 | 2-0 |
| Nov 26 | Utah or Washington (Great Alaska Shootout) |
L 96-91 | 2-1 |
| Nov 27 | Minnesota (Great Alaska Shootout) |
W 67-54 | 3-1 |
| Dec 1 | Coppin State | W 67-44 | 4-1 |
| Dec 8 | at Purdue | W 66-48 | 5-1 |
| Dec 11 | Northern Colorado | W 80-44 | 6-1 |
| Dec 18 | Duke (New York) |
L 78-67 | 6-2 |
| Dec 23 | Southwest Missouri State | W 61-53 | 7-2 |
| Dec 28 | Tulsa (Touchstone Energy All-College Classic) |
W 70-64 | 8-2 |
| Dec 30 | Florida A&M | W 104-45 | 9-2 |
| Jan 2 | Texas-Pan American | W 94-54 | 10-2 |
| Jan 8 | Colorado* | W 85-55 | 11-2 / 1-0 |
| Jan 10 | Connecticut | W 77-65 | 12-2 / 1-0 |
| Jan 15 | at Baylor* | W 65-61 | 13-2 / 2-0 |
| Jan 18 | at Texas A&M* | W 70-54 | 14-2 / 3-0 |
| Jan 22 | Texas* | W 64-60 | 15-2 / 4-0 |
| Jan 24 | Oklahoma State* | W 67-57 | 16-2 / 5-0 |
| Jan 29 | at Iowa State* | L 74-66 | 16-3 / 5-1 |
| Feb 1 | Texas A&M* | W 69-65 | 17-3 / 6-1 |
| Feb 5 | Texas Tech* | L 88-81 | 17-4 / 6-2 |
| Feb 6 | at Oklahoma State* | L 79-67 | 17-5 / 6-3 |
| Feb 12 | at Missouri* | L 68-65 | 17-6 / 6-4 |
| Feb 16 | Nebraska* | W 83-60 | 18-6 / 7-4 |
| Feb 19 | at Kansas State* | W 69-68 | 19-6 / 8-4 |
| Feb 21 | Kansas* | W 71-63 | 20-6 / 9-4 |
| Feb 26 | Baylor* | W 103-60 | 21-6 / 10-4 |
| Feb 28 | at Texas* | W 74-58 | 22-6 / 11-4 |
| Mar 5 | at Texas Tech* | W 74-54 | 23-6 / 12-4 |
| Mar 10 | Round One - Big 12 Championship | Bye | |
| Mar 11 | Quarterfinals - Big 12 Championship Missouri* |
W 83-79 | 24-6 / 13-4 |
| Mar 12 | Semifinals - Big 12 Championship Texas Tech* |
L 69-63 | 24-7 / 13-5 |
| Mar 17 | Round 1 - NCAA Tournament Niagara |
W 84-67 | 25-7 / 13-5 |
| Mar 19 | Round 2 - NCAA Tournament Utah |
L 67-58 | 25-8 / 13-5 |