| DATE | OPPONENT | SCORE | RECORD/BIG 12 |
| Aug 30 | North Texas | W 37-3 | 1-0 |
| Sept 6 | at Alabama | W 20-13 | 2-0 |
| Sept 13 | Fresno State | W 52-28 | 3-0 |
| Sept 20 | UCLA | W 59-24 | 4-0 |
| Oct 4 | at Iowa State* | W 53-7 | 5-0 / 1-0 |
| Oct 11 | Texas (at Dallas)* | W 65-13 | 6-0 / 2-0 |
| Oct 18 | Missouri* | W 34-13 | 7-0 / 3-0 |
| Oct 25 | at Colorado* | W 34-20 | 8-0 / 4-0 |
| Nov 1 | Oklahoma State* | W 52-9 | 9-0 / 5-0 |
| Nov 8 | Texas A&M* | W 77-0 | 10-0 / 6-0 |
| Nov 15 | Baylor* | W 41-3 | 11-0 / 7-0 |
| Nov 22 | at Texas Tech* | W 56-25 | 12-0 / 8-0 |
| Dec 6 | Kansas State* Big 12 Championship Kansas City |
L 35-7 | 12-1 / 8-1 |
| Jan 4 | LSU Nokia Sugar Bowl |
L 21-14 | 12-2 / 8-1 |